NOX, RAS and PKC-Δ as Key Players in Kidney Diseases: A Possible Role of Rottlerin
نویسنده
چکیده
ROS: Reactive Oxygen Species; RAS: Renin Angiotensin System; PKC-Δ: Protein Kinase C-Δ; NOX: NADPH Oxidase; BK Channels: Ca2+ Activated Potassium Channels; RAAS: Renin Angiotensin Aldosterone System; Caox: Calcium Oxalate; ACE2: Angiotensin-Converting Enzyme 2; Ang II: Angiotensin II; EMT: Epithelial To Mesenchymal Transition; AT1R :Ang II Type 1 Receptor; CKD: Chronic Kidney Disease; L-NAME: Nω-Nitro-LArginine Methyl Ester; AGE: Advanced Glycation End Products; ESRD: End Stage Renal Disease; COX: Cyclooxygenase; LO: Lipooxygenase
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